脑梗死患者脑血管狭窄程度与胰岛素抵抗的关系

目的：探讨胰岛素抵抗（IR）与脑血管狭窄的关系。方法：177例患者分为正常组，轻度狭窄组，中度狭窄组，重度及闭塞组，测定空腹血糖，胰岛素浓度，计算胰岛素敏感指数。结果：狭窄组患者FBG与FINS显著高于对照组（P〈0．01），ISI较正常组明显降低（P〈0．01）。且轻度组和中重度组的FINS、ISI之间比较差异有显著性（P〈0．05）。结论：急性脑梗死患者存在IR，并且IR程度与脑血管狭窄程度存在一定相关性，及早干预对于患者预后有重要意义，通过测定ISI，可作为脑血管造影前的一个参考指标。

Study of relationship between insulin resistance and cerebral artery stenosis

Objective:To study the relationship between insulin resistance(IR)and cerebral artery stenosis.Methods:The patients with acute cerebral infarction were chosen.The fasting plasma glucose(FPG),fasting insulin(FINS)were detected in four groups at the same time.The insulin sensitivity index(ISI),insulin resistance index were calclated.Then the data were entered into the computer and an-alyzed by SPSS13.0 statistic analysis software.Results:There were significant differences in FPG,FINS and ISI(P<0.05 or P<0.01)...