测定大肠癌患者的血清铁和血清铁蛋白的临床意义

目的 :探讨大肠肿瘤患者的血清铁和血清铁蛋白的表现。方法 :对 92例大肠癌的失血程度与癌的大小 ,部位 ,病程 ,病理和癌胚抗原之间的相关性进行对比。结果 :肿瘤直径大小 3cm组比小于等于 3cm组的血清铁 ,血清铁蛋白明显减少 (P <0 .0 1;P <0 .0 5 )。右半结肠组的失血量比左半结肠组的多 (P <0 .0 1)。结论 :大肠癌引起的失血与肿瘤的大小及发生部位有一定的关系

Significance of Serum Iron and Ferritin Levels in Patients with Colorectal Cancer

Objective: We investigated blood loss from colorectal cancer. Methods: In 92 men in relation to the size and site of the tumor. Dukes stage, pathologic type of cancer, and serum carcinoembryonic antigen positivity. We used indirect methods, measuring serum hemoglobin, iron and ferritin concentrations. Results: The means of these three concentrations were significantly lower in patients with a tumor >3cm than in those with a tumor <3cm in largest diameter (P<0.01; P<0.05). The means of the three values were lower in patients with proximal colon cancer than in those with distal colon cancer, but only the difference in serum hemoglobin concentration was significant. Cancers of the ulcerative type were found more often in the proximal colon (P< 0.01). Conclusion: These findings show that blood loss from colorectal cancer is closely related to the size and site of the tumor.