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泮托拉唑联合托烷司琼防治化疗所致消化道反应的临床观察
引用本文:杨牡丹,高峻.泮托拉唑联合托烷司琼防治化疗所致消化道反应的临床观察[J].中国医院药学杂志,2010(3).
作者姓名:杨牡丹  高峻
作者单位:山西省肿瘤医院;
摘    要:目的:观察泮托拉唑与托烷司琼+地塞米松联用治疗肿瘤化疗所致消化道反应的疗效。方法:将96例化疗所致难治性呕吐的患者随机分为2组,在下一周期化疗中泮托拉唑组给予泮托拉唑+托烷司琼+地塞米松,对照组给予托烷司琼+地塞米松。结果:泮托拉唑组在预防食欲不振,抑制恶心、呕吐等方面明显优于对照组(P均<0.05)。结论:泮托拉唑联合托烷司琼防治化疗药物所致消化道反应疗效较好,值得临床推广应用。

关 键 词:泮托拉唑  托烷司琼  化疗  消化道反应  

Clinical study of pantoprazole combined with tropisetron on prevention and cure of alimentary toxicities caused by tumor chemotherapy
YANG Mu-dan,GAO Jun.Clinical study of pantoprazole combined with tropisetron on prevention and cure of alimentary toxicities caused by tumor chemotherapy[J].Chinese Journal of Hospital Pharmacy,2010(3).
Authors:YANG Mu-dan  GAO Jun
Institution:YANG Mu-dan,GAO Jun(Shanxi Tumor Hospital,Shanxi Taiyuan 030013,China)
Abstract:OBJECTIVE To investigate the curative effect of pantoprazole combined with tropisetron for alimentary toxicities caused by tumor chemotherapy.METHODS Ninety-six cases involved in intractabe vomiting caused by tumor chemotherapy were divided into two groups at random on the second chemotherapy cycle.Fifty patients of pantoprazole group were treated with pantroprazole + tropisetron +dexathasone,and forty-six patients of control group were treated with tropisetron+dexathasone.RESULTS Pantoprazole group was sup...
Keywords:pantoreazole  tropisetron  chemotherapy  alimentary toxicities  
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