| 甲基莲心碱对照品的制备 |
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| 引用本文： | 刘韶,雷鹏,徐平声,肖菁.甲基莲心碱对照品的制备[J].中国现代医学杂志,2004,14(20):27-29. |
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| 作者姓名： | 刘韶 雷鹏 徐平声 肖菁 |
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| 作者单位： | 中南大学湘雅医院,药剂科,湖南,长沙,410008 |
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| 摘 要： | 目的制备甲基莲心碱对照品.方法柱层析分离,重结晶纯化甲基莲心碱,UV,IR,NMR,MS,HPLC及TLC等方法确定甲基莲心碱的结构和纯度.结果该方法得到的甲基莲心碱的纯度达到了98.85%.结论此甲基莲心碱对照品的纯度达到新药研究所需对照品的要求,且实验步骤较简单.
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| 关 键 词： | 甲基莲心碱 对照品 制备 |
Preparation of reference material of neferine |
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| Abstract.Preparation of reference material of neferine[J].China Journal of Modern Medicine,2004,14(20):27-29. |
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| Authors: | Abstract |
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| Abstract: | Objective: To investigate the preparation of the reference material of neferine. Methods: Column chromatography and recrystallization were adopted to isolate and purify neferine, while its structure and purity were determined by UV, IR, NMR, MS, TLC and HPLC analysis. Results: The purity of neferine prepared according to this method was 98.85%. Conclusion: The purity of neferine meets with the standard of the reference material, and the steps of the experiment are simple. |
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| Keywords: | neferine reference material preparation |
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