| 雷公藤微乳凝胶释药性能研究 |
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| 引用本文： | 管咏梅,赵益,陈丽华,王森,朱卫丰,刘红宁.雷公藤微乳凝胶释药性能研究[J].中国实验方剂学杂志,2010,16(17):1-3. |
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| 作者姓名： | 管咏梅 赵益 陈丽华 王森 朱卫丰 刘红宁 |
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| 作者单位： | 江西中医学院现代中药制剂教育部重点试验室,南昌,330004 |
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| 基金项目： | 十一五重大新药创制项目，江西省教育厅科学技术研究平台建设资助项目，2008年江西省卫生厅课题 |
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| 摘 要： | 目的:对雷公藤微乳凝胶的体外释药性能进行考察。方法:采用扩散池法,分别以半透膜和小鼠皮肤为透过介质,考察雷公藤微乳凝胶的透皮性能和释药速率。结果:雷公藤微乳凝胶体外释药规律以一级模型拟合较好,透皮速率约为2.6μg·cm-2·h-1。结论:雷公藤微乳凝胶中雷公藤甲素的体外透皮速率小于体外释放速率,表明该制剂属于缓释制剂。
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| 关 键 词： | 微乳凝胶 透皮性能 释药速率 |
| 收稿时间： | 7/1/2010 12:00:00 AM |
Study on Drug Releasing Property of Triptolide Microemulsion Gel in Vitro |
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| GUAN Yong-mei,ZHAO Yi,CHEN Li-hu,WANG Sen,ZHU Wei-feng and LIU Hong-ning.Study on Drug Releasing Property of Triptolide Microemulsion Gel in Vitro[J].China Journal of Experimental Traditional Medical Formulae,2010,16(17):1-3. |
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| Authors: | GUAN Yong-mei ZHAO Yi CHEN Li-hu WANG Sen ZHU Wei-feng and LIU Hong-ning |
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| Institution: | Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,China |
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| Abstract: | |
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| Keywords: | microemulsion gel percutaneous permeability the drug release rate |
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