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| 香椿叶总黄酮对糖尿病小鼠血糖的影响 | |
| 引用本文： | 张典,姜凤良,黄黎,陈有亮,邵玲巧,柴长斌,王粉侠,左晓春.香椿叶总黄酮对糖尿病小鼠血糖的影响[J].西北药学杂志,2011,26(4):270-271. |
| 作者姓名： | 张典 姜凤良 黄黎 陈有亮 邵玲巧 柴长斌 王粉侠 左晓春 |
| 作者单位： | 1. 西安医学院,陕西,西安,710021 2. 西安交通大学医学院,陕西,西安,710061 3. 陕西省友谊医院,陕西,西安,710068 |
| 摘 要： | 目的研究香椿叶总黄酮对糖尿病小鼠血糖的影响。方法采用链脲佐菌素腹腔注射制备糖尿病小鼠模型,造模成功小鼠随机分为模型组、香椿叶总黄酮大剂量(800 mg·kg-1·d-1)、中剂量(400 mg·kg-1·d-1)和小剂量组(100 mg·kg-1·d-1),优降糖组(60mg·kg-1·d-1),连续给药30 d后,观察血糖的变化。结果香椿总黄酮可明显降低糖尿病小鼠的血糖。结论香椿叶总黄酮有明显的降糖作用,为临床上防治糖尿病提供了理论依据。 |
| 关 键 词： | 香椿叶 黄酮类化合物 糖尿病小鼠 |
Effects of total flavonoid of Toona sinensis leaves on the blood glucose of diabetes mice |
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| ZHANG Dian,JIANG Fengliang,HUANG Li,CHEN Youliang,SHAO Lingqiao,CHAI Changbin,WANG Fenxia,ZUO Xiaochun.Effects of total flavonoid of Toona sinensis leaves on the blood glucose of diabetes mice[J].Northwest Pharmaceutical Journal,2011,26(4):270-271. | |
| Authors: | ZHANG Dian JIANG Fengliang HUANG Li CHEN Youliang SHAO Lingqiao CHAI Changbin WANG Fenxia ZUO Xiaochun |
| Institution: | ZHANG Dian1,JIANG Fengliang1,HUANG Li1,CHEN Youliang2,SHAO Lingqiao1,CHAI Changbin1,WANG Fenxia3,ZUO Xiaochun3(1.Xi'an Medical College,Shaanxi Xi'an 710021,China,2.School of Medicine,Xi'an Jiaotong University,Shaanxi Xi'an 710061,3.Shaanxi Friendship Hospital,Shaanxi Xi'an 710068,China) |
| Abstract: | Objective To study the effect of total flavonoid from Toona sinensis leaves on the blood glucose of diabetes mice.Methods The model mice of streptozotocin-diabetes were randomly divided into 5 groups： high dose group（800 mg·kg-1·d-1）,medium dose group（400 mg·kg-1·d-1）,low dose group（100 mg·kg-1·d-1）,model group and positive control group of phenformin（60 mg·kg-1·d-1）.All groups were fed qd for 30 consecutive days.Blood glucose was measured after 30 days.Results Total flavonoid from Toona sinensis leaves can decrease blood glucose on diabetes mice,which could provide a pharmacological basis on prevention and treatment of diabetes.Conclusion Total flavonoid from Toona sinensis leaves can decrease blood glucose of diabetes mice |
| Keywords: | Toona sinensis leaves flavonoid diabetic mice |
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