| 低分割立体定向放射治疗原发性视神经鞘脑膜瘤的疗效分析 |
| |
| 引用本文： | 穆晓峰,宁健,杨书明,赵水喜,杨远游,赵卫东,程海民,肖利华.低分割立体定向放射治疗原发性视神经鞘脑膜瘤的疗效分析[J].武警医学,2011,22(7):610-612. |
| |
| 作者姓名： | 穆晓峰 宁健 杨书明 赵水喜 杨远游 赵卫东 程海民 肖利华 |
| |
| 作者单位： | 武警总医院放疗中心,北京,100039;武警总医院眼眶病研究所,北京,100039 |
| |
| 摘 要： | 目的 评价在4 Gy×10次的剂量分割模式下,采用低分割立体定向放射治疗原发性视神经鞘脑膜瘤的近期疗效.方法 2004-8至2010-3本院收治的15例原发性视神经鞘脑膜瘤患者采用SGS-Ⅰ型超级伽玛刀进行低分割立体定向放射治疗,靶区处方剂量为40 Gy/4 Gy×10次,放疗结束后6个月进行随访,观察患者肿瘤控制率,临床症状改善情况及视力保存率.结果 经过中位时间23个月的随访,肿瘤控制率100%(15例),肿瘤最大径缩小超过50%的患者有4例.突眼症状改善率100%,治疗前后突眼度分别为(17.3±0.8) mm及(14.5±0.3) mm,P<0.01.全组视力保存率为73.3%(11/15),其中改善2例,稳定9例,下降2例,失明2例.有10例出现轻度的治疗相关反应,对症治疗后缓解.结论 原发性视神经鞘脑膜瘤接受处方剂量为40 Gy/4 Gy×10次低分割立体定向治疗,疗效确切,但视力改善率较低,甚至出现失明患者,对于剂量分割模式尚需进一步研究.
|
| 关 键 词： | 低分割立体定向放射治疗 原发性视神经鞘脑膜瘤 治疗效果 伽玛刀 |
| 收稿时间： | 2011-02-15 |
Analysis of therapeutic effect of fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma |
| |
| Mu Xiaofeng,Ning Jian,Yang Shuming,Zhao Shuixi,Yang Yuanyou,Zhao Wei dong,Cheng Haimin,Xiao Lihua.Analysis of therapeutic effect of fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma[J].Medical Journal of the Chinese People's Armed Police Forces,2011,22(7):610-612. |
| |
| Authors: | Mu Xiaofeng Ning Jian Yang Shuming Zhao Shuixi Yang Yuanyou Zhao Wei dong Cheng Haimin Xiao Lihua |
| |
| Institution: | Mu Xiaofeng~1,Ning Jian~1,Yang Shuming~1,Zhao Shuixi~1,Yang Yuanyou~1,Zhao Wei dong~1 Cheng Haimin~1,and Xiao Li-hua~2. 1.Department of Radiation Oncology,2.Institutes of Orbit Disease,General Hospital of the Chinese People's Armed Police Forces,Beijing 100039,China |
| |
| Abstract: | Objective To assess the efficacy of fractionated stereotactic conformal radiotherapy(SCRT) with target dose of 40Gy using 4Gy/fractionation in patients with primary optic nerve sheath meningioma(ONSM).Methods Between 2004 and 2010, 15 patients(15 eyes) with ONSM were treated by Hyper- SGSI gamma knife treatment system;All patients received SCRT with a median dose of 40 Gy in 10 fractionations.Clinical and radiographic follow- up were performed every 6 months after SCRT therapy,Efficacy of SCRT and improveme... |
| |
| Keywords: | hypofractionated stereotactic conformal radiotherapy primary optic nerve sheath meningioma treatment effect gamma knife |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《武警医学》浏览原始摘要信息 |
| 点击此处可从《武警医学》下载免费的PDF全文 |
|
