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醛固酮受体拮抗剂的降压治疗进展
引用本文:黄红娟. 醛固酮受体拮抗剂的降压治疗进展[J]. 心血管病学进展, 2011, 32(4): 565-568. DOI: 10.3969/j.issn.1004-3934.2011.04.032
作者姓名:黄红娟
作者单位:南京医科大学第一附属医院心内科,江苏,南京,210029
摘    要:醛固酮是肾素-血管紧张素-醛固酮系统的终末环节,在原发性高血压、顽固性高血压中起重要作用.醛固酮受体拮抗剂在高血压治疗方面的作用越来越受到重视.现综述醛固酮在高血压中的病理生理作用,醛固酮受体拮抗剂的分类、降压机制及临床应用进展等.

关 键 词:醛固酮  醛固酮受体拮抗剂  高血压  治疗

Advances in Aldosterone Receptor Antagonists on Hypertension
HUANG Hong-juan. Advances in Aldosterone Receptor Antagonists on Hypertension[J]. Advances in Cardiovascular Diseases, 2011, 32(4): 565-568. DOI: 10.3969/j.issn.1004-3934.2011.04.032
Authors:HUANG Hong-juan
Affiliation:HUANG Hong-juan,LU Xin-zheng (Department of Cardiology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)
Abstract:The hormone aldosterone is the final product of the renin angiotensin aldosterone system,which contributes significantly to primary and sustained hypertension.Increasingly attention is being given to the role aldosterone has in influencing blood pressure.This review shows the pathophysiology of aldosterone,its classification and mechanism,and clinical uses of aldosterone receptor antagonist.
Keywords:aldosterone  aldosterone receptor antagonist  hypertension  treatment  
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