| 急性心肌梗死早期患者3种血清测定及意义 |
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| 引用本文： | 黄爱群,严跃红,钟玉婷.急性心肌梗死早期患者3种血清测定及意义[J].检验医学与临床,2011,8(12):1461-1462. |
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| 作者姓名： | 黄爱群 严跃红 钟玉婷 |
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| 作者单位： | 1. 广州医学院港湾医院检验科,510700
2. 广州医学院港湾医院内科,510700 |
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| 摘 要： | 目的探讨血清肌酸激酶同工酶-MB(CK-MB)、肌红蛋白(Myo)和人心肌肌钙蛋白I(CTnI)检测在急性心肌梗死(AMI)早期诊断中的意义。方法以40例健康体检者作对照,检测85例高度疑为AMI的患者在发病6 h内检测3个血清指标水平。比较其对AMI诊断的性能,以进行优化组合检测。结果 AMI患者在发病6 h内,CK-MB、Myo和CTnI的敏感性分别为82.35%、100.00%和92.64%;特异性分别为94.74%、89.47%和100.00%;单项比较:敏感度和阴性预期值以Myo最高,特异度、阳性预期值和可靠性则以CTnI最佳;并联组合比较:敏感度、特异度、阳性预期值和阴性预期值均以CTnI与Myo最理想;可靠性则以CTnI与CK-MB联合最好;串联组合比较:5项指标均以CTnI与Myo串联检测为最佳。结论血清CTnI在AMI早期诊断中具有良好的灵敏度、特异性和可靠性。CTnI和Myo联合检测可提高对AMI早期诊断的性能。
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| 关 键 词： | 急性心肌梗死 肌酸激酶同功酶 肌红蛋白 人心肌肌钙蛋白I |
Determination of three serum indicators in patients with early AMI and its significance |
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| HUANG Ai-qun,YAN Yue-hong,ZHONG Yu-ting.Determination of three serum indicators in patients with early AMI and its significance[J].Laboratory Medicine and Clinic,2011,8(12):1461-1462. |
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| Authors: | HUANG Ai-qun YAN Yue-hong ZHONG Yu-ting |
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| Institution: | HUANG Ai-qun1,YAN Yue-hong2,ZHONG Yu-ting1(1.Department of Clinical Laboratory,2.Department of Internal Medicine,Harbour Hospital of Guangzhou Medical College,Guangzhou,Guangdong 510700,China) |
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| Abstract: | Objective To investigate the significance of serum creatine kinase isoenzyme-MB(CK-MB),myoglobin(Myo)and cardiac troponin I(CTnI)in the early diagnosis of acute myocardial infarction(AMI).Methods 40 healthy persons were as control group,and the serum levels of CK-MB,Myo and cTnI in 85 cases of highly suspicious patients with AMI in 6 hours after clinical symptoms were tested,then we compared the performance of diagnosis of AMI in order to optimize the combination of detection.Results The sensitivities of cT... |
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| Keywords: | acute myocardial infarction creatine kinase isoenzyme-MB Myoglobin cardiac troponin I |
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