术中磁共振和功能神经导航在语言功能区病变手术的应用

摘要：目的探讨术中磁共振和功能神经导航在语言区病变手术中的应用价值。方法61例右利手患者在术中磁共振和基
于血氧水平依赖和弥散张量成像技术的功能神经导航辅助下实施语言功能区病变手术，按部位分为A组（左额下回后部
附近病变）和B组（左颞上回后部附近病变），术前及术后2周用西方失语症成套试验对所有患者进行语言评估，获得失语
指数（AQ）。结果AQ术前正常者（AQ≥93.8）33例，AQ术后与AQ术前对比无统计学差异（P>0.05），AQ术前低于正常者28例，AQ
术后较术前对比有所提高（P<0.01）。术后2周时，14例（23.0%）出现语言功能下降，仅有2例（3.2%）在6个月随访时仍存
在语言功能障碍。41例获得全切除，20例获得次全切除，AQ变化值（ΔAQ=AQ术后-AQ术前）与病变切除程度无关，A组ΔAQ
高于B组。结论术中磁共振和功能神经导航技术能够较好显示病变与语言相关皮层及纤维束之间的关系，有助于语言
功能区病变患者术后语言功能的保留。

Application of intraoperative magnetic resonance imaging and functional neuronavigation in microsurgery for lesions near language-related brain regions

Objective To explore the clinical value of intraoperative magnetic resonance imaging(MRI) and functional neuronavigation in the preservation of the language function during microsurgery for lesions near language-related brain regions.Methods Sixty-one right-handed patients underwent microsurgical resection of the lesions near the language-related brain regions with the assistance of intraoperative MRI and blood oxygen level-and diffusion tensor imaging-based functional neuronavigation.The patients were divi...