Two cases of hematuria with hemoglobin C trait |
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Authors: | John David Spencer John T. Sanders Bettina H. Ault |
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Affiliation: | (1) Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA;(2) Division of Nephrology, University of Tennessee Health Science Center, Memphis, TN, USA;(3) Children’s Foundation Research Center at Le Bonheur Children’s Medical Center, Memphis, TN, USA;(4) Department of Pediatrics, Children’s Foundation Research Center, University of Tennessee Health Science Center, 50 North Dunlap, Room 301, Memphis, TN 38103, USA; |
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Abstract: | Patients with sickle cell disease commonly experience painless hematuria. Hematuria may be found in patients with sickle cell trait, sickle cell anemia, and sickle cell hemoglobin C disease, but it is believed to be uncommon in patients with other hemoglobinopathies, such as hemoglobin C disease and hemoglobin C trait. We report two cases of children with hemoglobin C trait who presented with persistent painless hematuria. Because it is possible that hematuria in a patient with hemoglobin C trait is purely coincidental, all patients with a hemoglobinopathy and hematuria should undergo a complete evaluation so as not to overlook other causes of hematuria. |
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