Polypurine reverse Hoogsteen hairpins as a gene therapy tool against survivin in human prostate cancer PC3 cells in vitro and in vivo |
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| Authors: | Laura Rodrí guez,Xenia Villalobos,Sheila Dakhel,Laura Padilla,Rosa Hervas,Jose Luis Herná ndez,Carlos J. Ciudad,Vé ronique Noé |
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| Affiliation: | 1. Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, 08028 Barcelona, Spain;2. Biomed Division of LEITAT Technological Center, 08028 Barcelona, Spain |
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| Abstract: | |
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| Keywords: | aODN, antisense oligonucleotide CRPC, castration-resistant prostatic cancer DOTAP, N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate EMSA, electrophoretic mobility shift assay MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide NE, nuclear extract PPRHs, Polypurine Reverse Hoogsteen hairpins |
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