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高效薄层扫描法测定愈肝扶正胶囊中黄芪甲苷含量
引用本文:王荣,赵兴红,胡晓丽. 高效薄层扫描法测定愈肝扶正胶囊中黄芪甲苷含量[J]. 中国药学杂志, 1999, 0(2): 114-116
作者姓名:王荣  赵兴红  胡晓丽
作者单位:1. 兰州730020兰州军区后勤部药物研究所
2. 兰州730020兰州军区医学高等专科学校教务部
摘    要: 目的:研究愈肝扶正胶囊质量控制方法。方法:运用高效薄层扫描法对该制剂中黄芪甲苷的含量进行测定。结果:薄层色谱斑点清晰,黄芪甲苷在2~12μg范围内浓度与峰面积线性关系良好r=0.9994,平均回收率为98.9%,RSD为2.00%。结论:建立的测定愈肝扶正胶囊中黄芪甲苷含量的方法简便、可靠,重现性好,可作为该制剂质量控制方法。.

关 键 词:愈肝扶正胶囊  高效薄层扫描法  黄芪甲苷  质量控制
收稿时间:1998-01-08;

Quality control of Yugan Fuzheng capsule with HPTLCS
Wang Rong,Zhao Xinghong,Hu Xiaoli. Quality control of Yugan Fuzheng capsule with HPTLCS[J]. Chinese Pharmaceutical Journal, 1999, 0(2): 114-116
Authors:Wang Rong  Zhao Xinghong  Hu Xiaoli
Affiliation:(Wang R),Zhao Xinghong(Zhao XH),Hu Xiaoli(Hu XL
Abstract:OBJECTIVE:To provide a method of quality control for Yugan Fuzheng capsule (preparation of Chinese materia medica). METHOD:High performance thin-layer chromatographic scanning (HPTLCS) was used for the determination of astragaloside Ⅳ in the preparation. RESULTS: The spots of astragaloside Ⅳ on the HPTLCS plate had a good linearity between its content and area within the range of 2~12μg(r=0.9994).The average recovery was 98.9%,and the RSD was 2.00%. CONCLUSION: This qualitative determination for astragaloside Ⅳ can be used as quality control because of its convenience,accuracy and good reproducibility.
Keywords:Yugan Fuzheng capsule  high performance thin-layer chromatogramphy scanning  quality control
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