中老年2型糖尿病甲状腺结节患病情况调查

目的:观察中老年2 型糖尿病(T2DM)甲状腺结节的患病情况。方法:528 例T2DM 患者(T2DM组)的空腹血糖、糖化血红蛋白、甲状腺彩超检查结果,并与同期参加体检的312名中老年健康人群(对照组)作比较。结果:T2DM组患者甲状腺结节的总患病率为 57.58%,高于对照组的45.83%(P<0.01),且以多发结节为主。男性和女性70~岁组患者甲状腺结节患病率均高于50~岁组(P<0.05),但不同病程的患者甲状腺结节患病率差异无统计学意义(P>0.05)。女性T2DM 患者甲状腺结节患病率为63.30%,高于男性患者的50.22%(P<0.01)。糖化血红蛋白<7%和≥7%患者的甲状腺结节患病率差异无统计学意义(P>0.05)。logistic 多因素回归分析显示,甲状腺结节的发生可能与年龄、性别和糖尿病独立相关。结论:中老年T2DM 患者的甲状腺结节患病率较高,可能对病情和预后有一定影响,应加以重视,予以筛查。

Survey of thyroid nodules in elderly patients with type 2 Diabetic

Objective:To investigate the incidence of thyroid nodules in elderly patients with type 2 diabetic. Methods:The fasting blood-glucose,glycosylated hemoglobin and high-resolution ultrasonography of 528 elderly patients with type 2 diabetes (T2DM group) and 312 healthy controls ( control group ) were detected and compared. Results:The total prevalence rate of thyroid nodules was 57. 58% in the T2DM group,which was higher than that of the control group (45. 83 %)(P<0. 01);and multiple nodules were most often seen. The incidence of thyroid nodules in the group over 70 was higher than that in the group over 50 in both the male and the female(P<0. 05),while there was no statistical significance in different diabetic periods(P >0. 05). Thyroid nodules were more commonly seen in the female (63. 30%) than in the male (50. 22%)(P<0. 01);The prevalence rate of thyroid nodules demonstrated that there was no statistical significance between patients with glycosylated hemoglobin < 7% and ≥7% (P > 0. 05). Logistic regression analysis showed that age,gender and diabetes were independent risk factors for thyroid nodules. Conclusions:The incidence of thyroid nodules is higher in elderly patients with type 2 diabetic than in the normal control. As the disease may affect the prognosis and treatment of T2DM,special attention and screening should be directed to those patients.