银丹心脑通联合阿司匹林对缺血性脑卒中患者神经功能及血液流变学的影响

目的:观察并分析银丹心脑通联合阿司匹林对于缺血性脑卒中患者神经功能和血液流变学指标的影响。方法:选取缺血性脑卒中患者80例，按照随机数字表法分为观察组和对照组，各40例。对照组患者采取常规治疗方法，观察组患者采取银丹心脑通联合阿司匹林。比较2组患者治疗前后的美国国立卫生研究院卒中量表（NIHSS）、改良Rankin量表（MRS）评分、Barthel指数以及血液流变学相关指标和2组患者的临床治疗效果。结果:观察组患者的治疗效果优于对照组（P<0.05），观察组患者治疗后的NIHSS评分和MRS评分均显著低于对照组（P<0.01），Barthel指数高于对照组（P<0.05）；观察组患者治疗后的血液流变学指标红细胞比容、红细胞沉降率、全血黏度、红细胞沉降率方程K值、血浆黏度、全血还原黏度、纤维蛋白原均低于对照组（P<0.05~P<0.01）。结论:银丹心脑通联合阿司匹林能显著改善缺血性脑卒中患者的神经功能和血液流变学的各项指标，值得临床推广应用。

Yindan Xinnaotong combined with aspirin on the influence of neural function and hemorheology in patients with stroke

Objective:To observe and analyze effect of Yindan Xinnaotong combined with aspirin on the hemorheology indexes in stroke patients. Methods:Eighty stroke patients were selected and randomly divided into the observation group(n=40) and the control group(n=40). The patients of the observation group were given Yindan Xinnaotong combined with aspirin,the patients of the control group were given conventional therapy. NIHSS score, MRS score, Barthel index and the related parameters of hemorheology were observed and compared before and after treatment in both groups, the clinical total effective rate of two groups of patients were compared. Results:Observation group of patients in the treatment of effective was significantly higher than control group(P<0. 05), after treatment,the observation group of patients of NIHSS score and MRS score was significantly lower than control group(P<0. 01), Barthel index was significantly higher than control group(P<0. 05),the observation group of patients:the hemorheology indexes of red blood cells deposited,blood sedimentation,whole blood viscosity,plasma viscosity,blood sedimentation equation K value,whole blood reduction viscosity,fibrinogen were significantly lower than that of control group(P <0. 05 to P <0. 01). Conclusions:Yindan Xinnaotong combined with aspirin can significantly improve neural function and all the indexes of hemorheology in patients with stroke, worthy of clinical popularization and application.