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通脉生骨Ⅱ号方对激素性股骨头缺血性坏死BGP及VEGF表达的影响
引用本文:梁周,王大伟,陆兰兰,龙朝阳,陈双辉,陈明科. 通脉生骨Ⅱ号方对激素性股骨头缺血性坏死BGP及VEGF表达的影响[J]. 西部中医药, 2012, 25(10): 44-46
作者姓名:梁周  王大伟  陆兰兰  龙朝阳  陈双辉  陈明科
作者单位:梁周 (广西中医药大学,广西,南宁,530001) ; 王大伟 (广西中医药大学附属瑞康医院骨科) ; 陆兰兰 (广西中医药大学,广西,南宁,530001) ; 龙朝阳 (广西中医药大学,广西,南宁,530001) ; 陈双辉 (广西中医药大学,广西,南宁,530001) ; 陈明科 (广西中医药大学,广西,南宁,530001) ;
基金项目:2010年广西研究生教育创新计划资助项目
摘    要:目的:探讨中药通脉生骨II号方对实验性兔BGP及VEGF表达的影响。方法:将45只健康成年雄性新西兰大白兔随机分成空白组,模型组,对照组,汤剂组4组,观察治疗前后BGP及VEGF的表达。结果:各组BGP及VEGF值治疗前后有显著性差异。结论:通脉生骨Ⅱ号方对家兔激素性股骨头坏死预防、治疗作用方面优于盐酸川芎嗪碱,有显著的防治效果。

关 键 词:股骨头坏死  激素性  通脉生骨Ⅱ号方  BGP  VEGF  实验研究

Influence of TongMai ShengGu Recipe II on Expressions of BGP and VEGF in Glucocorticoid-induced Avascular Necrosis of Femoral Head
LIANG Zhou,WANG Da-wei,△,LU Lan-lan,LONG Zhao-yang,CHEN Shuang-hui,CHEN Ming-ke. Influence of TongMai ShengGu Recipe II on Expressions of BGP and VEGF in Glucocorticoid-induced Avascular Necrosis of Femoral Head[J]. Western Journal of Traditional Chinese Medicine, 2012, 25(10): 44-46
Authors:LIANG Zhou  WANG Da-wei    LU Lan-lan  LONG Zhao-yang  CHEN Shuang-hui  CHEN Ming-ke
Affiliation:1 Guangxi University of Chinese Medicine,Nanning 530001,China; 2 Ruikang Hospital of Guangxi Traditional Chinese Medical University
Abstract:Objective: To approach the influence of TongMai ShengGu recipe II on BGP and VEGF in experimental rabbits.Method: Forty-five healthy rabbits were randomly divided into blank group,model group,control group and decoction group,to observe expressions of BGP and VEGF before and after treating.Result: There are remarkable differences before and after treating in BGP and VEGF among different groups.Conclusion: TongMai ShengGu recipe II is better than ligustrazine in preventing and treating glucocorticoid-induced necrosis of femoral head, showing remarkable preventive effect.
Keywords:necrosis of femoral head, glucocorticoid-induced  TongMcd ShengGu recipe II  BGP  VEGF  experimental study
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