| HIV/AIDS合并乙型肝炎病毒和(或)丙型肝炎病毒感染的研究进展 |
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| 引用本文： | 陈超,游晶,杨微波,李俊敏. HIV/AIDS合并乙型肝炎病毒和(或)丙型肝炎病毒感染的研究进展[J]. 中国全科医学, 2012, 15(9): 955-958 |
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| 作者姓名： | 陈超 游晶 杨微波 李俊敏 |
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| 作者单位： | 昆明医学院第一附属医院感染性疾病科,云南省昆明市,650032 |
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| 基金项目： | 国际合作项目--中国盖茨艾滋病项目 |
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| 摘 要： | 乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)及人类免疫缺陷病毒(HIV)具有相似的传播途径,均可通过血液、性接触及母婴传播。因此,在HIV感染者中常合并HBV、HCV感染。这为人们预防和治疗HIV/人类获得性免疫缺陷综合征(AIDS)合并HBV、HCV感染带来了巨大的挑战。随着高效抗逆转录病毒治疗(HAART)的广泛应用,肝脏相关性疾病已成为HIV感染者主要的合并症和死亡原因。本文就目前HIV/AIDS合并HBV、HCV感染的流行病学、相互影响、治疗等方面进行综述。
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| 关 键 词： | 人类免疫缺陷病毒 获得性免疫缺陷综合征 肝炎病毒,乙型 肝炎病毒,丙型 混合感染 重叠感染 |
Research Progress on HIV/AIDS Coinfection/Superinfection with HBV and/or HCV |
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| Affiliation: | CHEN Chao,YOU Jing,YANG Wei-bo,et al.Department of Infectious Diseases,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China |
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| Abstract: | Human immunodeficiency virus(HIV) coinfection and/or superinfection with hepatitis B virus(HBV) and hepatitis C virus(HCV) are very common because of their shared ways of viral transmission.They are mainly spread through exposure to contaminated blood or blood products,sexual contact and mother-to-child transmission.It poses a huge challenge for prevention and treatment of the HIV/AIDS coinfection and/or superinfection with HBV and/or HCV.With the extensive application of highly active antiretroviral therapy(HAART),liver-related disease has become the main complication and causes of death in HIV/AIDS patients.This review will give a detailed introduction of the epidemiology of HIV/AIDS coinfection and/or superinfection with HBV and/or HCV,as well as characteristics of each virus and their interaction and strategies for treatment. |
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| Keywords: | Human immunodeficiency virus Acquired immunodeficiency syndrome Hepatitis B virus Hepatitis C virus Coinfection Superinfection |
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