Hepatocellular carcinoma,a unique tumor with a lack of biomarkers |
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| Institution: | 1. Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, The Netherlands;2. Department of Medicine, University of Minnesota, Minneapolis, MN, USA;3. Universidad San Francisco de Quito, Hospital Eugenio Espejo, Quito, Ecuador;4. Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil;5. Centro de Enfermedades Hepaticas y Digestivas (CEHYD), Bogota, Colombia |
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| Abstract: | Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Interestingly, the great majority of individuals affected by the tumor have underlying liver disease, therefore narrowing the population to be screened. Still, however, there is a clear lack of blood biomarkers, and surveillance in those at risk is performed by frequent imaging of the liver. A variety of multinational collaborations are currently invested in finding biomarkers for HCC based on liver-produced proteins. A new approach with assessment of peripheral proteins might be necessary for the successful early detection of this malignancy. |
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| Keywords: | HCC Biomarkers Blood |
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