The use of marine-derived bioactive compounds as potential hepatoprotective agents |
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| Authors: | Dileep G Nair Ralf Weiskirchen Salma K Al-Musharafi |
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| Affiliation: | 1.Department of Applied Biotechnology, Sur College of Applied Sciences, Ministry of Higher Education, Sur, Sultanate of Oman;2.Institute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital Aachen, Aachen, Germany |
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| Abstract: | The marine environment may be explored as a rich source for novel drugs. A number of marine-derived compounds have been isolated and identified, and their therapeutic effects and pharmacological profiles are characterized. In the present review, we highlight the recent studies using marine compounds as potential hepatoprotective agents for the treatment of liver fibrotic diseases and discuss the proposed mechanisms of their activities. In addition, we discuss the significance of similar studies in Oman, where the rich marine life provides a potential for the isolation of novel natural, bioactive products that display therapeutic effects on liver diseases. |
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| Keywords: | liver fibrosis hepatoprotective agent marine compound Scytonemin Pacifenol Epitaondiol Stypotriol Contignasterol Xestobergsterol Clathriol Hymenialdisine Hyrtiosal |
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