Fidaxomicin Therapy in Critically Ill Patients with Clostridium difficile Infection |
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| Authors: | Samuel Penziner Yanina Dubrovskaya Robert Press Amar Safdar |
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| Affiliation: | New York University Langone Medical Center and New York University School of Medicine, New York, New York |
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| Abstract: | Fidaxomicin use to treat proven Clostridium difficile infection (CDI) was compared between 20 patients receiving care in critical care units (CCUs) and 30 patients treated on general medical floors. At baseline, the CCU patients had more initial CDI episodes, more severe and complicated disease, and more concurrent broad-spectrum antibiotic coverage. On multivariate analysis, the response to fidaxomicin therapy among the critically ill patients was comparable to that among patients in the general medical wards. |
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