| D-核糖对实验性心肌缺血和心律失常的作用研究 |
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| 引用本文： | 刘平怀 符健 黄川 吴红红. D-核糖对实验性心肌缺血和心律失常的作用研究[J]. 中国药业, 2005, 14(10): 26-28 |
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| 作者姓名： | 刘平怀 符健 黄川 吴红红 |
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| 作者单位： | 海南大学理工学院，海南天王生物制药技术开发中心，海南天王生物制药技术开发中心，海南天王生物制药技术开发中心 海南 海口 570228，海南 海口 570314，海南 海口 570314，海南 海口 570314 |
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| 摘 要： | 目的:观察D-核糖的抗心肌缺血和心律失常作用.方法:应用大鼠实验性冠状动脉缺血性心肌梗塞模型和药物诱发动物冠状动脉缺血和心律失常模型.结果:D-核糖对实验性冠状动脉缺血性心肌梗塞所致的心肌酶增高有较好的抑制作用,可明显抑制肾上腺素等药物诱发的冠状动脉缺血或心律失常,明显延长乌头碱引起的大鼠呼吸和心跳停止时间.结论:D-核糖对实验性心肌缺血和心律失常具有较好的治疗作用.
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| 关 键 词： | D-核糖 抗心肌缺血 心律失常 |
| 文章编号： | 1006-4931（2005）10-0026-02 |
| 收稿时间： | 2004-12-10 |
| 修稿时间： | 2005-03-28 |
Research of Anti- myocardial Ischemia and Anti- arrhythmia Cordis Effect of D- ribose |
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| Liu Pinghuai, Fu Jian, Huang Chuan, Wu Honghong. Research of Anti- myocardial Ischemia and Anti- arrhythmia Cordis Effect of D- ribose[J]. China Pharmaceuticals, 2005, 14(10): 26-28 |
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| Authors: | Liu Pinghuai Fu Jian Huang Chuan Wu Honghong |
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| Abstract: | Objective: To study the anti - myocardial ischemia and anti - arrhythmia cordis effect of D - ribose. Methods: To apply experimental rats model of coronary artery blood - deficiency myocardial infarction and coronary artery blood - deficiency and arrhythmia cordis caused by drugs. Results: D - ribose reduced high - LDH and CK caused by experimental coronary artery blood - deficiency myocardial infarction, inhibited coronary artery blood - deficiency and arrhythmia cordis caused by drugs such as adrenaline, and prolonged the duration of respiration and heartbeat caused by aconitine. Conclusion: D - ribose has better therapeutic effects on experimental myocardial ischemia and arrhythmia cordis. |
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| Keywords: | D - ribose anti - myocardial ischemia arrhythmia cordis |
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