重复性经颅磁刺激治疗卒中后失语的研究进展

失语是脑卒中后常见的并发症，严重影响患者的生活质量。通常卒中后失语的治疗以药物、语言康复训练和中医理疗为主，但疗效不佳或个体差异大。越来越多的研究证实作为一种非侵入性大脑刺激技术———重复性经颅磁刺激技术（rTMS）可为卒中后失语患者语言功能的康复提供一种新的治疗手段。本文就rTMS治疗卒中后失语的可能性，rTMS治疗卒中后失语的现状以及rTMS治疗卒中后失语的可能机制展开综述。着重阐述了目前国内外开展rTMS治疗卒中后失语的治疗模式、刺激参数和治疗效果，并从神经重塑的角度探讨了双侧半球，特别是非优势半球在接受rTMS治疗后发生的变化及其对卒中后失语患者语言能力的影响。旨在为rTMS治疗卒中后失语的进一步应用及对其作用机制的进一步研究提供参考。

Research progress on applying repetitive transcranial magnetic stimulation to post-stroke aphasia

Aphasia is a common complication of stroke , which affects a person′s quality of life devastatingly .While pharmacological treatments , professionally administered speech-language therapy and physical therapy of traditional Chinese medicine are commonly employed treatment of stroke induced aphasia , their therapeutic effects are quite variable and are generally modest .Increasing evidences suggest that repetitive transcranial magnetic stimulation （ rTMS） as a non-invasive brain stimulation technique has shown promise as potential approaches for enhancing aphasia recovery .In this review, we first examined the possibility of employing rTMS to post-stroke language recovery .Then,we discussed the current state and the possible mechanism of employing rTMS as research tools in patients who experienced post -stroke aphasia .We reviewed the therapeutic protocol ,stimulation parameters and the therapeutic result in papers detailedly .We also discussed the contributions from the dominant and non-dominant hemispheres after rTMS .This paper aimed to provide a reference to a further application and its mechanism of rTMS to post -stroke language recovery.