缺血性卒中急性期血糖水平对卒中病情和预后的影响

目的 探讨急性缺血性卒中患者血糖水平变化与临床病情严重程度以及预后的关系。方法 按入院次日清晨血糖水平，将196例急性缺血性卒中患者分成血糖升高组49例，血糖正常组147例，观察血糖与梗死部位、病灶大小、病情程度以及预后的关系。结果 高血糖的发生与急性缺血性卒中患者病灶部位、临床病情严重程度以及梗死病灶的大小有关，高血糖多见于大脑中线部位梗死及临床症状严重的缺血性卒中患者。血糖升高组患者预后明显差于血糖正常组。结论 高血糖可能加剧急性缺血性卒中患者神经系统损伤，血糖水平的高低可作为判断病情轻重和预后的重要参数。

Impacts of Blood Glucose Levels on Clinical Manifestation and Prognosis of Acute Cerebral Infarction

Objective To explore the dynamic changes of the levels of blood glucose and its relationship withclinical manifestation and prognosis in patients with acute cerebral infarction.Methods According to the levels of blood glucose, 196 cases with acute cerebral infarction were divided into two groups. 49 patients were in the group of elevated blood glucose and the rest 147 were in the group of normal blood glucose. The relationship of the blood glucose levels with thelesion location, the lesion size, the severity and the prognosis of cerebral infarction were investigated.Results There existed the relationship between elevated blood glucose levels and the location, the size and severity of lesions. Elevated blood glucose levels were more found in the parts of the brain midline infarction and severe cases. The prognosis of patients with elevated blood glucose level wasworse than that of the patients with normal blood glucose levels.Conclusion Hyperglycemia may cause neurological deterioration during acute cerebral infarction. The level of blood glucose can be used as an important parameter of the severity and prognosis of cerebral infarction.