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紫外法测定硫酸阿托品眼膏的含量
引用本文:常雪君,文莉敏.紫外法测定硫酸阿托品眼膏的含量[J].黑龙江医药科学,2002,25(5):47-47.
作者姓名:常雪君  文莉敏
作者单位:1. 泰兴市人民医院药剂科,江苏泰兴,225400
2. 鹤岗人民医院,黑龙江,鹤岗,154100
摘    要:目的:建立硫酸阿托品眼膏的含量测定的紫外分光光度方法。方法:用无水乙醇提取后,在258nm测定吸光度。结果:在0.3~1.1mg/ml范围内,吸光度与硫酸阿托品的浓度间线性关系良好(r>0.999)。模拟样品的平均回收率为99.9%~100.4%,相对标准差为0.61%~1.1%。结论:本法简单、准确,可用于硫酸阿托品眼膏的测定。

关 键 词:硫酸阿托品  眼膏  紫外分光光度法  含量测定
文章编号:1008-0104(2002)05-0047-01
修稿时间:2002年2月25日

Determination of Atropine sulfate eye ointment by spectrophotometry
CHANG Xuejun,WEN Limin.Determination of Atropine sulfate eye ointment by spectrophotometry[J].Heilongjiang Medicine and Pharmacy,2002,25(5):47-47.
Authors:CHANG Xuejun  WEN Limin
Institution:CHANG Xuejun1 WEN Limin2
Abstract:Objective: A UV spectrophotometry for the determination of Atropine sulfate eye ointment was established. Method: After extracting with absolute ethanol, Atropine sulfate was determined at wavelength 258 nm. Results: The absorbance and concentration showed better linear relation between 0.3 mg/ml to 1.1 mg/ml (r>0.999). The average recovery of simulated sample was 99.9% to 100.4%, with related standard difference of 0.61% to 1.1%. Conclusion: The established method is simple and accurate. It is suitable for the determination of Atropine sulfate eye ointment
Keywords:Atropine sulfate  eye ointment  UV spectrophotometry  determination  
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