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克林霉素磷酸酯注射液与盐酸氨溴索注射液的配伍稳定性考察
引用本文:陈伯文,沈惠明,周琴,尚尔宁.克林霉素磷酸酯注射液与盐酸氨溴索注射液的配伍稳定性考察[J].临床和实验医学杂志,2006,5(9):1305-1306.
作者姓名:陈伯文  沈惠明  周琴  尚尔宁
作者单位:苏州市立医院,江苏,苏州,215002;苏州市立医院,江苏,苏州,215002;苏州市立医院,江苏,苏州,215002;苏州市立医院,江苏,苏州,215002
摘    要:目的 研究克林霉素磷酸酯注射液与盐酸氨溴索注射液的配伍稳定性.方法 用生理盐水将克林霉素磷酸酯注射液与盐酸氨溴索注射液混合,放置6 h,观察外观、PH值变化,并以旋光法测定克林霉素磷酸酯的含量,用紫外分光光度法测定盐酸氨溴索的含量,观察配伍液含量的变化.结果 两药配伍液在6 h内外观,含量,PH值均无明显变化.结论 6 h内两药配伍稳定,性质无明显改变.

关 键 词:克林霉素磷酸酯  盐酸氨溴索  配伍  稳定性
修稿时间:2006年7月25日

Study on stability of Clindamycin Phosphate injection and Ambroxol Hydrochloride injection
CHEN Bo-wen,SHEN Hui-ming,ZHOUQin,et al..Study on stability of Clindamycin Phosphate injection and Ambroxol Hydrochloride injection[J].Journal of Clinical and Experimental Medicine,2006,5(9):1305-1306.
Authors:CHEN Bo-wen  SHEN Hui-ming  ZHOUQin  
Institution:CHEN Bo-wen,SHEN Hui-ming,ZHOUQin,et al.Su zhou Municipal Hospital,Suzhou Jiangsu 215002 China.
Abstract:Objective To study the compatible stability of Clindamycin Phosphate Injection and Ambroxol Hydrochloride Injection in the Sodi-um Chloride Injection.Methods The contents were determined after mixing of Clindamycin Phosphate Injection and Ambroxol Hydrochloride In-jection within 6 hours, and the appearance of the solution was observed and its PHvalue was determined. Polarimeter method was adopted in Clin-damycin Phosphate Injection and UV-spectro photometry method was adopted in Ambroxol Hydrochloride Injection.Results The compatibility of Clindamycin Phosphate Injection and Ambroxol Hydrochloride Injection had no significant change in the aspect ,PH,and content.Conclusion The Clindamycin Phosphate Injection could be combined with Ambroxol Hydrochloride Injection, and used within 6 h.
Keywords:Clindamycin Phosphate  Ambroxol Hydrochloride  Compatibility  Stability
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