八段锦对糖尿病患者糖脂代谢干预效果的Meta分析＊

目的 系统评价八段锦对糖尿病患者糖脂代谢水平的影响。方法 系统检索国内外数据库,纳入有关八段锦治疗糖尿病的随机对照试验进行荟萃分析。结果 本研究共纳入16项研究,包括1185例糖尿病患者,其中试验组共591例,对照组共594例。Meta分析结果显示：①糖代谢方面：疗程不足6个月时,八段锦组糖尿病患者的FPG（MD = -0.60,95%CI[-0.98,-0.23]）、HbA1c（MD = -0.8,95%CI[-0.99,-0.61]）改善情况优于对照组;疗程达6个月时,八段锦组糖尿病患者的FPG（MD = -1.07,95%CI[-1.67,-0.47]）、P2hPG（MD = -1.2,95%CI[-2.31,-0.08]）、HbA1c（MD = -0.73,95%CI[-1.14,-0.32]）改善程度优于对照组。②脂代谢方面：疗程不足6个月时,八段锦组糖尿病患者的TC（MD = -0.79,95%CI[-1.13,-0.45]）、HDL（MD = 0.21,95%CI[0.12,0.29]）改善情况优于对照组;疗程达6个月时,八段锦组糖尿病患者的TC（MD = -0.46,95%CI[-0.71,-0.20]）、TG（MD = -0.60,95%CI[-1.14,-0.06]）、HDL（MD = 0.21,95%CI[0.09,0.33]）改善情况优于对照组。结论 作为辅助治疗手段,八段锦具有进一步改善糖尿病患者糖脂代谢水平的作用,尤其在FPG、HbA1c、TC、HDL方面的疗效较为稳定,同时安全性较好,具有良好的推广应用价值。

Meta-analysis of Intervention Effect of Baduanjin on Glucose and Lipid Metabolism in Diabetic Patients

Meta-analysis of Intervention Effect of Baduanjin on Glucose and Lipid Metabolism in Diabetic PatientsZhu Shengling1, Wang Chuanchi2**, He Jiali1, He Liu1(1. Guangdong hospital of Traditional Chinese Medicine; 2. Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China)Abstract: Objective: To evaluate the effect of Baduanjin on glucose and lipid metabolism in diabetic patients. Methods: The domestic and foreign databases were systematically searched, and the randomized controlled trials of Baduanjin in the treatment of diabetes were included for meta-analysis. Results: A total of 16 studies were included in this study, including 1185 diabetic patients, 591 in the experimental group and 594 in the control group. Meta-analysis results show: (1) Glucose metabolism: when the treatment course is less than 6 months, the improvement of FPG(MD = -0.60, 95% CI [-0.98,-0.23]), HbA1c(MD = -0.8, 95% CI [-0.99,-0.61]) in Baduanjin group is better than that in the control group; After 6 months of treatment, the improvement of FPG(MD = -1.07, 95% CI [-1.67,-0.47]), P2hPG(MD = -1.2, 95% CI [-2.31,-0.08]), HbA1c(MD = -0.73, 95% CI [-1.14,-0.32]) and HbA1c (MD =-0.73, 95% CI [-0.32]) in Baduanjin group are better than those in the control group. (2) Lipid metabolism: when the course of treatment is less than 6 months, the improvement of TC(MD = -0.79, 95% CI [-1.13,-0.45]), HDL(MD = 0.21, 95% CI [0.12, 0.29]) in Baduanjin group is better than that in the control group; After 6 months of treatment, the improvement of TC(MD = -0.46, 95% CI [-0.71,-0.20]), TG(MD = -0.60, 95% CI [-1.14,-0.06]), HDL(MD = 0.21, 95% CI [0.09, 0.33]) in Baduanjin group is better than that in the control group. Conclusion: As an adjuvant therapy, Baduanjin has the effect of further improving glucose and lipid metabolism level of diabetic patients, especially in FPG, HbA1c, TC, HDL, with stable curative effect, good safety and good popularization and application value.Key words: Baduanjin; Diabetes; Systematic Review; Meta Analysis; Glucose Metabolism; Lipid Metabolism