科技人员血脂水平与心血管疾病的关系

目的：研究科技人员的血脂水平及其与冠心病、脑卒中和糖尿病的关系。方法：对中国科学院的2万余名科技人员进行了心血管流行病学调查，统计冠心病、脑卒中和糖尿病病史的阳性率，分析有无冠心病、脑卒中和糖尿病病史的两部分人群的总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL－C）和高密度脂蛋白胆固醇（HDL－C）的水平及血脂异常 的检出率。结果：科技人员血脂水平较高，有冠心病、脑卒中和糖尿病病中者的TC、TG、LDL－C的水平高于无这些疾病史的对照人群，其中TC、TG有显著性差异（P＜0．01），这些心血管病患者的HDL－C低于对照人群（P＜0．01）；有冠心病，脑卒中和糖尿病病史者的高TC、TG、LDL－C和你HDL－C的检出率谪于对照人群，特别是有冠心病病史者（P＜0．01）。有无这些心血管疾病中我的两部分人群的血脂水平有部分重叠，即使无这些疾病中的科技人员的血脂异常的比例也较高。结论：北京科技人员人群的血脂异常的比例较高，较高水平TG、TG和LDL－C及较低水平的HDL－C是冠心病、脑卒中和糖尿病的危险因素。

The Association between Serum Lipids and Cardiovascular Diseases in Intellectual Population in Beijing

Objective To identify associations between serum lipids and coronary disease, diabetes and stroke in intellectual population in Beijing. Methods A cross section survey was performed in around 20 000 intellectual individuals in Chinese Academy of Sciences. Serum levels of TC, TG, HDL C,LDL C and prevalence of different kinds of dyslipidemia among individuals with and without history coronary disease, diabetes and stroke were analyzed. Results Levels of serum TC, TG, HDL C and LDL C in intellectual population were higher than those in community residents. Individuals with coronary disease, diabetes, or stroke had higher levels of TG and TC ( P <0 01) as well as LDL C, and higher prevalence of different kinds of dyslipidemia ( P <0 01) but lower level of HDL C than that of controls ( P <0 01). Conclusion Associations between serum lipids and coronary disease, diabetes and stroke illustrated that higher TC, TG and LDL C and lower HDL C were risk factors for cardiovascular diseases.