| 冠脉康胶囊对大鼠血栓模型及小鼠急性脑缺血模型的影响 |
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| 引用本文： | 李显华,邹桂新,杜佳林,包玉龙,袁媛. 冠脉康胶囊对大鼠血栓模型及小鼠急性脑缺血模型的影响[J]. 实用中医内科杂志, 2012, 0(18): 20-21 |
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| 作者姓名： | 李显华 邹桂新 杜佳林 包玉龙 袁媛 |
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| 作者单位： | 辽宁省中医药研究院 |
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| 基金项目： | 辽宁省科学技术资金200325007 |
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| 摘 要： | [目的]复制大鼠血栓模型及小鼠急性脑缺血模型,观察冠脉康胶囊对大鼠血栓模型及对小鼠急性脑缺血模型的影响。[方法]采用结扎大鼠左肾下方下腔静脉致血栓模型形成法,观察冠脉康胶囊抗血栓形成作用;采用小鼠断头缺血模型,观察冠脉康胶囊抗急性脑缺血作用。[结果]冠脉康胶囊能减轻血栓模型大鼠的血栓重量,增加小鼠张口呼吸次数,延长小鼠张口呼吸时间。[结论]冠脉康胶囊具有抗血栓形成、抗急性脑缺血作用。
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| 关 键 词： | 冠脉康胶囊 血栓模型 脑缺血模型 实验研究 |
The Effect on Rat Thrombosis model and Mouse Acute Cerebral Ischemia model of Guanmaikang Capsule |
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| LI Xianhua,ZOU Guixin△,DU Jialin,BAO Yulong,YUAN Yuan. The Effect on Rat Thrombosis model and Mouse Acute Cerebral Ischemia model of Guanmaikang Capsule[J]. , 2012, 0(18): 20-21 |
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| Authors: | LI Xianhua ZOU Guixin△ DU Jialin BAO Yulong YUAN Yuan |
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| Affiliation: | (Liaoning Academy of Traditional Chinese Medicine,Shenyang 110034,China) |
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| Abstract: | [Objective] To observe the effect on rat thrombosis model and mice acute cerebral ischemia model of Guanmaikang capsule with the replication of rat thrombosis and acute cerebral ischemia in mice model.[Method] Using the ligation of rat left kidney inferior vena cava formation method to observe anti-thrombotic effect and using the decapitation ischemia model to observe the effect on acute cerebral ischemia of Guanmaikang capsule.[Result] Guanmaikang capsule can reduce thrombus weight,extend breathing time and frequency.[Conclusion] Guanmaikang capsule has the antagonistic effect on thrombosis and acute cerebral ischemia. |
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| Keywords: | Guanmaikang capsule Thrombosis model Cerebral ischemia model Experimental study |
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