| 胸腺肽α1配合血浆置换治疗慢性乙型重型肝炎的效果观察 |
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| 引用本文： | 潘志敏,刘光俊,王兴,王军,曹灵芝.胸腺肽α1配合血浆置换治疗慢性乙型重型肝炎的效果观察[J].实用肝脏病杂志,2011,14(4):273-274. |
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| 作者姓名： | 潘志敏 刘光俊 王兴 王军 曹灵芝 |
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| 作者单位： | 江苏省扬州市第三人民医院感染病科,225006 |
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| 摘 要： | 目的观察胸腺肽α1配合人工肝血浆置换治疗慢性乙型重型肝炎患者的效果。方法 48例慢性乙型重型肝炎患者在常规治疗的基础上给予胸腺肽α1配合血浆置换治疗,观察疗效。结果患者治疗后TBIL、ALT、血氨均有非常显著性降低（P〈0.01）,血清HBV DNA定量极显著降低（P〈0.005）,ALB、PTA均有明显升高（P〈0.05或P〈0.01）;治疗后半年随访,存活34例（70.8%）。结论胸腺肽α1配合血浆置换治疗慢性乙型重型肝炎安全、有效。
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| 关 键 词： | 慢性乙型重型肝炎 血浆置换 胸腺肽α1 治疗 |
Safety and efficacy of thymosin α1 and plasma exchange in treatment of patients with chronic severe hepatitis B |
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| PAN Zhimin,LIU Guangjun,Wang Xing,et al..Safety and efficacy of thymosin α1 and plasma exchange in treatment of patients with chronic severe hepatitis B[J].Journal of Clinical Hepatology,2011,14(4):273-274. |
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| Authors: | PAN Zhimin LIU Guangjun Wang Xing |
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| Institution: | PAN Zhimin,LIU Guangjun,Wang Xing,et al.Department of Infectious Diseases,The Third People's Hospital,Yangzhou 225006,Jiangsu Province,China |
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| Abstract: | Objective To evaluate the therapeutic effect of thymosin α1 and plasma exchange in patients with chronic severe hepatitis B.Methods Conventional treatments combined with thymosin α1 and plasma exchange in 48 patients with chronic severe hepatitis B were observed.Results After treatment,the symptoms of the patients improved significantly;The TBIL,ALT and HBV DNA were reduced obviously(P<0.01,P<0.01,P<0.01),while ALB and PTA increased(P<0.05,P<0.01).34(70.8%)survived.Conciusion Thymosin α1 and plasma exchange in treatment of patients with chronic hepatitis B are safe and effective. |
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| Keywords: | Hepatitis B Plasma exchange Thymosin α1 Treatment |
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