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口服避孕药与缺血性脑卒中关系的Meta分析
引用本文:史新竹,梁多宏,张莹,李青,张金生. 口服避孕药与缺血性脑卒中关系的Meta分析[J]. 现代预防医学, 2008, 35(23): 4562-4565
作者姓名:史新竹  梁多宏  张莹  李青  张金生
作者单位:1. 沈阳医学院公共卫生学院流行病教研室,沈阳,110034
2. 岫岩满族自治县卫生局
摘    要:[目的]研究口服避孕药与缺血性脑卒中之间的关系。[方法]检索Pub Med等数据库中1990年以来公开发表的脑卒中与口服避孕药的相关文献,按照所制定的纳入标准筛选,最终确定15篇符合条件的国外病例-对照研究文献,并运用RevMan4.2软件,对其中的数据应用随机效应模型和固定效应模型进行综合的定量分析。[结果]口服避孕药与缺血性脑卒中合并OR值为1.54,95%CI为1.11~2.14。[结论]使用口服避孕药可能是缺血性脑卒中的危险因素。

关 键 词:缺血性脑卒中  口服避孕药:Meta分析

META ANALYSIS ON RELATIONSHIP BETWEEN ORAL CONTRACEPTIVES AND ISCHEMIC STROKE
SHI Xin-zhu,LIANG Duo-hong,ZHANG Ying,et al.. META ANALYSIS ON RELATIONSHIP BETWEEN ORAL CONTRACEPTIVES AND ISCHEMIC STROKE[J]. Modern Preventive Medicine, 2008, 35(23): 4562-4565
Authors:SHI Xin-zhu  LIANG Duo-hong  ZHANG Ying  et al.
Abstract:[Objective] To research the relationship between oral contraceptives and ischemic stroke. [ Methods] Searched PubMed for articles published from 1990 about the relationship between OC and ischemic stroke. Basing on the criteri-a, 15 papers with case-control study were selected and analyzed with RevMan4.2. Random effect model and fixed effect model were used for data synthesis. [Results] The pooled OR value about the relationship between OC and ischemic stroke was 1.54, 95%CI was 1.11-2.14. [Conclusion] OC could be a risk factor of ischemic stroke.
Keywords:Ischemic stroke  Oral contraceptives  Meta-analysis
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