| 多吉美治疗6例晚期转移性肾癌的初步疗效观察 |
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| 引用本文： | 王德林,吴小候,蒲军,何云峰,唐伟,陈在贤,李曾.多吉美治疗6例晚期转移性肾癌的初步疗效观察[J].重庆医学,2009,38(17). |
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| 作者姓名： | 王德林 吴小候 蒲军 何云峰 唐伟 陈在贤 李曾 |
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| 作者单位： | 重庆医科大学附属第一医院泌尿外科,400016 |
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| 摘 要： | 目的 初步评价多吉美(sorafenib)治疗晚期转移性肾癌的疗效和安全性.方法 对2008年2月至2009年5月本院6例晚期转移性肾癌患者连续口服多吉美400mg,2次/天,并观察其疗效.结果 4例患者肿瘤转移灶体积均明显缩小(PR),1例肺转移灶完全消失(CR),1例髂骨转移灶缩小3个月后开始稍增大,但未大于或等于20%或出现新病灶(SD).结论 多吉美能有效地抑制转移性肾癌生长,显著延缓其进展,延长晚期转移性肾癌患者生存时间.
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| 关 键 词： | 肾癌 多吉美 靶向治疗 |
Initial therapeutic effect of sorafenib for metastatic renal cell carcinoma:report of 6 cases |
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| WANG De-lin,WU Xiao-hou,PU Jun,et al..Initial therapeutic effect of sorafenib for metastatic renal cell carcinoma:report of 6 cases[J].Chongqing Medical Journal,2009,38(17). |
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| Authors: | WANG De-lin WU Xiao-hou PU Jun |
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| Institution: | WANG De-lin,WU Xiao-hou,PU Jun,et al.(Department of Urology,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China) |
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| Abstract: | Abjective To evaluate the initial therapeutic effect of sorafenib for metastatic renal cell carcinoma.Methods The patient with metastatic renal cell carcinoma was taken sorafenib,at the dosage of 400 mg,two times per day.Results The metastatic tumor volume of 4 cases with advanced renal cell carcinoma significantly decreased(PR),and 1 dispeared completely(CR),1 progressed moderately after 3 months(SD).Conclusion Sorafenib can suppress tumor growth efficiently in metastatic renal cell carcinoma,postpone its ... |
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| Keywords: | renal cell carcinoma sorafenib targeted therapy |
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