超声应变显像在房间隔缺损封堵术中的应用

目的 应用超声应变显像技术(SI)评价房间隔缺损(ASD)封堵术前、术后心脏功能的变化.方法 选取接受Amplataer封堵器治疗的继发孔型ASD病人50例,分别于ASD封堵术前3 d、术后1周、术后3个月,应用SI在心尖四腔切面测量各房室腔大小、肺动脉收缩压(PASP),右室侧壁三尖瓣环处、右室侧壁中部、室间隔二尖瓣环处、室间隔中部、左室侧壁二尖瓣环处以及左室侧壁中部收缩期峰值应变(Ss).选择健康志愿者50例作为对照组.结果 与对照组比较,ASD组右心房(RA)横径、右心室(RV)横径、PASP增大,差异有显著性(t=2.23～2.87,P＜0.05);与术前比较,术后1周RA横径、 RV横径、 PASP显著减小,术后3个月RA横径、 RV横径、PASP进一步减小,差异有显著性(F=7.58～13.46,q=3.50～3.98,P＜0.05).与对照组比较,ASD组术前右室壁和室间隔、左室侧壁二尖瓣环处Ss显著增大,差异有显著性(t=2.04～2.97,P＜0.05).与封堵术前比较,术后1周右室侧壁、室间隔中部Ss均显著降低(F=8.57～14.66,q=3.67～4.90,P＜0.05),术后3个月右室侧壁、室间隔和左室壁Ss均显著降低(q=3.46～3.86,P＜0.05);与封堵术后1周比较,术后3个月右室侧壁中部Ss显著降低(F=14.59,q=3.46,P＜0.05).结论 SI可准确、定量评价房间隔缺损封堵术前、术后心脏功能的变化,评价封堵术的治疗效果.

APPLICATION OF STRAIN IMAGING IN PATIENTS UNDERGOING ATRIAL SEPTAL DEVICE CLOSURE

Objective To assess cardiac function by strain imaging(SI) in patients with atrial septal defects(ASD) undergoing device closure. Methods Fifty patients with secondary isolated ASD undergoing device closure and 50 healthy controls were enrolled in this study.Using SI technique,the transverse diameters(TD) of all chambers and pulmonary artery systolic pressure(PASP) were measured at the apex of heart,and the systolic strain peaks(SSPs) were measured in tricuspid annulus,middle part of right ventricle(RV),mit...