| IKK与糖尿病肾病 |
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| 引用本文： | 马晓红,刘素筠. IKK与糖尿病肾病[J]. 医学综述, 2007, 13(7): 539-541 |
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| 作者姓名： | 马晓红 刘素筠 |
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| 作者单位： | 山西医科大学第二附属医院内分泌科,太原,030001 |
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| 摘 要： | 糖尿病肾病是糖尿病微血管病并发症,是目前引起糖尿病患者致死致残的主要原因之一。NF-κB作为一种核转录因子,调节众多基因的表达,参与糖尿病肾病的发生和发展。IκB激酶(IKK)是NF-κB激活过程中的关键酶,通过作用于IKK达到治疗疾病的目的可作为一个研究方向。
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| 关 键 词： | 糖尿病肾病 IκB激酶 核因子-κB |
| 文章编号： | 1006-2084（2007）07-0539-03 |
| 收稿时间： | 2006-03-21 |
| 修稿时间： | 2006-03-212007-02-25 |
IKK and Diabetic Nephropathy |
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| MA Xiao-hong,LIU Su-jun. IKK and Diabetic Nephropathy[J]. Medical Recapitulate, 2007, 13(7): 539-541 |
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| Authors: | MA Xiao-hong LIU Su-jun |
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| Affiliation: | Department of Endocrinology , The Second Hospital of Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Diabetic nephropathy is a diabetic microangiopathy complication,which is also the main cause of diabetic death and mutilation.Nuclear factor kappaB is a kind of nuclear factor ,which regulate the expression of many gene and ,and participate the occurrence and development of diabetic nephropathy.IκB kinase(IKK)is a key enzyme in the process of activation of NF-KB,it may be a promising method to treat diabete by affecting IKK. |
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| Keywords: | Diabetic nephropathy IκB kinase Nuclear factor-kappaB |
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