Abstract: | AbstractSilver stains are commonly used in histology laboratories to demonstrate a variety of tissue substances. With the passage of time. it has become evident that several of the chemicals used in silver stains, as well as silver compounds themselves, pose hazards to laboratory workers. Disposal of these chemicals also poses a problem.This article briefly outlines some of the hazards of working with the chemicals used in silver stains. A comprehensive chemical hygiene plan, which must be developed for each laboratory, provides a standard operating procedure for working safely with chemicals. Material safety data sheets provide information on each chemical used in the laboratory and must be available. The use of several of the chemicals employed in silver stains is covered by Federal, state, and local laws. The state and local laws may be more stringent than the Federal laws. (The J Histotechnol 19:197, 1996) |