3.0 T MRI对中脑导水管脑脊液流动的研究

目的应用MR相位对比法分析对照组、梗阻性脑积水组(脑积水组)中脑导水管平面脑脊液流量、流速及流动曲线。材料与方法对照组30例,脑积水组16例,均应用3.0 T MR扫描仪、相位对比电影序列对导水管平面脑脊液进行定性观察和定量测定。结果对照组导水管平面脑脊液呈与心脏搏动相关的双向节律性流动。对照组脑脊液流动曲线呈平滑倒"U"形29例,波浪形1例。脑积水组呈欠规则倒"U"形1例,波浪形15例。对照组头侧与足侧脑脊液平均流量分别为(0.0311+0.0201)ml/s、(0.0366+0.0196)ml/s,流速分别为(4.027+1.174)cm/s、(4.107+1.433)cm/s脑积水组头侧与足侧脑脊液平均流量分别为(0.0070+0.0069)ml/s、(0.0078+0.0044)ml/s,流速分别为(0.550+0.327)cm/s、(0.599+0.606)cm/s。两组头侧与足侧脑脊液平均流量、流速两两比较均具有统计学义(P0.05)。结论 MR相位对比法能显示导水管平面脑脊液的流动节律,流速。对照组、脑积水组导水管平面的脑脊液流动节律、头侧及足侧的脑脊液平均流量、流速均不同。

Cine-PC MRI in the evaluation of cerebrospinal lfuid lfow dynamics

Objectives: Motion of the cerebrospinal lfuid (CSF) in aqueduct of sylvius was examined in volunteers and a number of patients with abnormalities of the CSF circulation with MRI in phase contrast cine mode (Mm cine PC). Materials and Methods: Control group 30 cases hydrocephalus group 16 cases on a Philips Achieva 3.0 T X-series MRI unit were displayed. Quantitative evaluation of CSF lfow via phase reconstruction permits a more precise mapping of the intracranial and intraspinal lfow patterns is more sensitive in detecting fluid motion and allows calculation of CSF velocity and lfow volume.Results: Aqueduct cerebrospinal lfuid of control group is associated with cardiac pulsation the lfow type of control group is bi-directional lfat rhythmic flow. In control group ,the cerebrospinal fluid flow curve was the smooth inverted u" type ,and in hydrocephalus group the curve was wave type. The average CSF lfow of the head and foot side in the control group were (0.0311+0.0201) ml/s and (0.0366+0.0196) ml/s, the velocities were (4.027+1.174) cm/s, (4.107+1.433) cm/s, respectively. In hydrocephalus group, the average CSF lfow of the head and foot side were (0.0070+0.0069) ml/s and (0.0078+0.0044) ml/s, the velocities were (0.550+0.327) cm/s, (0.606+0.599) cm/s respectively. The comparisons of the average lfow velocity between two groups have statistics meaning (P<0.05).Conclusions: Cine PC MRI, is capable of demonstrating both normal and abnormal intracranial and intraspinal CSF lfow. Such a study can be easily added as an extra pulse sequence at the end of a routinely acquked MR exam.