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术中放疗结合增敏剂顺铂治疗食管癌21例初步报告
引用本文:孙玉鹗,陈国雄.术中放疗结合增敏剂顺铂治疗食管癌21例初步报告[J].解放军医学杂志,1993,18(2):101-103.
作者姓名:孙玉鹗  陈国雄
作者单位:解放军总医院胸外科,解放军总医院胸外科,解放军总医院胸外科,解放军总医院胸外科,解放军总医院胸外科放疗科,解放军总医院胸外科放疗科,解放军总医院胸外科放疗科,解放军总医院胸外科麻醉科 100853,100853,100853,100853,100853,100853,100853,100853
摘    要:

关 键 词:食管肿瘤  放射疗法  外科手术  顺铂

INTRAOPERATIVE RADIATION THERAPY COMBINED WITH RADIOSENSITIZING AGENT CISPLATIN FOR ESOPHAGEAL CANCER
Sun Yu'e,Cui Zhonghou,Zhou Naikang,Xu Qiming,Chen Guoxong,Chang Qingsen,Feng Linchun,Song Yunqing.INTRAOPERATIVE RADIATION THERAPY COMBINED WITH RADIOSENSITIZING AGENT CISPLATIN FOR ESOPHAGEAL CANCER[J].Medical Journal of Chinese People's Liberation Army,1993,18(2):101-103.
Authors:Sun Yu'e  Cui Zhonghou  Zhou Naikang  Xu Qiming  Chen Guoxong  Chang Qingsen  Feng Linchun  Song Yunqing
Institution:Sun Yu'e,Cui Zhonghou,Zhou Naikang,Xu Qiming,Chen Guoxong,Chang Qingsen,Feng Linchun,Song Yunqing. Department of Thoracic Surgery,General Hospital of CPLA,Beijing 100853
Abstract:Intraoperative radiation therapy (IORT) was done in 21 patients with esophageal cancer from May 1991 to December 1991. A radiation dose of 15-20 GY was delivered before esophagectomy to the tumor and peritumoral tissue. Intravenous and peritumoral injection of 10-20mg cisplatin was performed 4 hours before operation and prior to IORT respectively. External irradiation of 40-60GY(8- 16Mev photon beam)was delivered to the mediastinum after recovery from surgery. The postoperative course was uneventful and no complications developed in all patients. The clinical significance, technique, indications, doses and possible complications of IORT and the use of radiosensitizing agent cisplatin were discussed.
Keywords:Esophageal cancer  Intraoperative radiation therapy
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