365例胸痹心痛患者证型与血脂分析

目的]了解胸痹心痛患者的血脂和中医证型间的关系。方法]对365例胸痹心痛患者进行辨证,并检查血脂,对 比研究证型与血脂间的关系。结果]365例胸痹心痛患者有278例至少有一项血脂异常,87例血脂正常;血脂异常组和正 常组各证型分布无显著性差异(P>0.05);血瘀证患者的平均高密度脂蛋白(HDL)低于非血瘀证,痰浊证患者的HDL低 于非痰浊证,血清甘油三酯(TG)高于非痰浊讧;随着证型的复杂化,血清总胆固醇(TC)和低密度脂蛋白(LDL)水平 升高;证型虚实与血脂无关。结论]胸痹心痛不一定与血脂增高有关,虚实证均可发生,但以血瘀证和疾浊证的血脂异常 较为明显。

Relationship Between Blood Lipid Levels and Syndrome Patterns in 365 Cases of Qi-obstruction Chest Pain

Objective] To investigate the relationship between blood lipid levels and syndrome patterns in the cases of Qi-obstruction chest pain. Methods] Three hundred and sixty-five cases of Qi-obstruction chest pain were differentiated according to the theory of traditional Chinese medicine and the blood lipids levels in these cases were also detected. Results] Among the cases, 278 were with at lease one of the blood lipid indexes at abnormal level, 87 with all indexes at normal; the difference of syndrome patterns was insignificant in the cases with normal and abnormal blood lipid ( P > 0.05); the average high-density lipoprotein (HDL) level was lower in blood-stasis cases than that in non-blood-stasis cases; HDL level was lower while serum triglyceride (TG) level higher in turbid-phlegm (TP) cases than those in non-TP cases; serum total cholesterol (TC) and low-density lipoprotein (LDL) levels were increased with the complication of syndrome patterns. The syndrome of deficiency type or of excess type had no correlation with the blood lipid levels. Conclusion] Syndrome patterns in Qi-obstruction chest pain, no matter deficiency type or excess type, has no certain correlation with the increase of blood lipid levels; however, the abnormal blood lipid levels usually exist in the pattern of blood stasis and in that of turbid phlegm.