Belgian collaborative study of the in-vitro susceptibility of the Bacteroides fragilis group |
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Authors: | Y Glupczynski A Belgian Collaborative Study Group |
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Institution: | (1) Department of Microbiology, Brugmann University Hospital, Avenue J.-J. Crocq, 1 - B 1020 Brussels, Belgium;(2) Department of Microbiology, Brugmann University Hospital, Avenue J. J. Crocq, 1, B 1020 Brussels, Belgium |
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Abstract: | The antimicrobial susceptibility of clinical isolates of the Bacteroides fragilis group obtained from nine large Belgian university and community hospitals was studied. Of the -lactam antibiotics tested, none were active against 100% of the isolates. Piperacillin was active against 93% of the strains at a breakpoint of 64 lag/ml. The percentage of isolates inhibited at 16 g/ml (and 32 g/ml) for the 7-alpha-methoxy antibiotics was: cefoxitin 84 94]; latamoxef 87 93]; and cefotetan 64 79]. B. fragilis tended to be more susceptible to all -lactams than the other members of the group.Among the non -lactam antibiotics, the resistance rate for minocycline, doxycycline, clindamycin and erythromycin (at a breakpoint of 4 g/ml) were l%, 4%, 14% and 34%, respectively. Like the -lactams, clindamycin was less active against non B. fragilis species of the group.Chloramphenicol, metronidazole and tinidazole were still active against 100% of the isolates at their breakpoint values (8 lag/ml). |
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Keywords: | B fragilis Antimicrobial susceptibility |
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