Toxoplasmacidal activity of macrophages activated by recombinant major surface antigen (P30) of Toxoplasma gondii. |
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| Authors: | A Makioka and A Kobayashi |
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| Institution: | Department of Parasitology, Jikei University School of Medicine, Tokyo, Japan. |
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| Abstract: | Recombinant major surface antigen (P30), which was produced as a glutathione S-transferase (EC 2.5.1.18) fusion protein of Toxoplasma gondii, was found to be able to activate macrophages to kill T. gondii in vitro. The macrophage activation was due to P30 in the fusion protein, not to glutathione S-transferase. |
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