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Treatment failure of nosocomial pertussis infection in a very-low-birth-weight neonate
Authors:Bonacorsi Stéphane  Farnoux Caroline  Bidet Philippe  Caro Valérie  Aizenfisz Sophie  Benhayoun Mounir  Aujard Yannick  Guiso Nicole  Bingen Edouard
Affiliation:Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris 7, Service de Microbiologie, Paris, France.
Abstract:We describe a case of nosocomial maternal transmission of Bordetella pertussis to a very-low-birth-weight (VLBW) neonate in whom treatment was unsuccessful. This case underscores the need for rapid and sensitive PCR diagnosis in VLBW neonates and in parents with clinical signs of pertussis and suggests that standard treatment may not be appropriate for VLBW neonates.
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