Treatment failure of nosocomial pertussis infection in a very-low-birth-weight neonate |
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Authors: | Bonacorsi Stéphane Farnoux Caroline Bidet Philippe Caro Valérie Aizenfisz Sophie Benhayoun Mounir Aujard Yannick Guiso Nicole Bingen Edouard |
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Affiliation: | Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris 7, Service de Microbiologie, Paris, France. |
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Abstract: | We describe a case of nosocomial maternal transmission of Bordetella pertussis to a very-low-birth-weight (VLBW) neonate in whom treatment was unsuccessful. This case underscores the need for rapid and sensitive PCR diagnosis in VLBW neonates and in parents with clinical signs of pertussis and suggests that standard treatment may not be appropriate for VLBW neonates. |
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