| 肾衰宁颗粒延缓大鼠慢性肾功能衰竭的实验研究 |
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| 引用本文： | 张宇. 肾衰宁颗粒延缓大鼠慢性肾功能衰竭的实验研究[J]. 辽宁中医药大学学报, 2009, 0(5) |
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| 作者姓名： | 张宇 |
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| 作者单位： | 辽宁中医药大学; |
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| 摘 要： | 目的:探讨肾衰宁颗粒对慢性肾功能衰竭(CRF)大鼠肾组织的病理学研究。方法:采用5/6肾切除造模方法复制大鼠的CRF模型,随机分为正常组、模型组、肾衰宁颗粒组、大黄组。测定各组大鼠灌胃前、灌胃后60天的体重、Scr、BUN、Hb及24h尿蛋白定量值,光镜下观察肾组织形态学变化。结果:肾衰宁颗粒能显著降低CRF大鼠Scr、BUN、24h尿蛋白定量,升高其Hb。结论:肾衰宁颗粒能有效降低CRF,对改善试验性慢性肾衰有较明显的药效作用。
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| 关 键 词： | 慢性肾功能衰竭 动物模型 肾衰宁颗粒 |
Exoerimental Research on Delaying Rats' Chronic Renal Failure with Shenshuaining Pellet |
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| ZHANG Yu. Exoerimental Research on Delaying Rats' Chronic Renal Failure with Shenshuaining Pellet[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2009, 0(5) |
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| Authors: | ZHANG Yu |
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| Affiliation: | Liaoning University of TCM;Shenyang 110032;Liaoning;China |
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| Abstract: | Objective:Investigate the effects of Shenshuaining Pelleton renal pathomorphology. Methods:Randomly divide the rats induced to chronic renal failure(CRF) animal model by 5/ 6nephrectomy(classic Platt method) group has 10 rats. Examine each rat's weight,Scr,BUN,Hb,value before intragastric administration and after 60 days' intragastric administration. Results:Shenshuaining Pelletcan obviously reduce the CRF rats' Scr,BUN value increase their Hbvalue. Conclusion:Shenshuaining Pellet can have an effect to redu... |
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| Keywords: | chronic renal failure animal experiment Shenshuaining pellet |
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