15055例拟受血者血液传播疾病血清指标的分析

目的探讨拟受血者输血前各项血液传播性疾病血清标志物情况。方法对15 055例拟受血者血液传播疾病血清指标进行分析,采用酶联免疫吸附试验(ELISA)对拟受血者进行丙型肝炎病毒抗体(抗-HCV)和人类免疫缺陷病毒抗体(抗-HIV)检测;梅毒螺旋体(抗-TP)检测采用ELISA、明胶颗粒凝集试验和快速血浆反应素环状卡片试验(RPR)3种方法检测。结果抗-HCV阳性率为1.67%,抗-HIV阳性率0.03%。单独ELISA检测抗-TP阳性、ELISA和RPR检测抗-TP均阳性、单独RPR检测抗-TP阳性率分别为2.76%、0.58%和0.03%。15例同时抗-HCV和抗-TP阳性。结论做好输血前血液传播疾病检测,不仅可以了解该地区血源性疾病的感染情况,还可减少和避免医疗纠纷及医源性感染,保证医患双方的合法权益。

Analysis on serum markers of transfusion-transmitted diseases in 15055 blood recipients before transfusion

Objective To explore the detection results of transfusion-transmitted diseases（TTD）serum markers in blood recipients before transfusion.Methods Anti-HCV and Anti-HIV were detected by ELISA before transfusion.Syphilis antibody（Anti-TP） were detected by ELISA,TPPA and RPR.Results The positive rates of anti-HCV and Anti-HIV were 1.67% and 0.03% respectively.The positive rates of Anti-TP were2.76% only by ELISA,0.58% by ELISA and RPR together,0.03% only by RPR.There were 15 patients which anti-HCV and anti-TP was positive.Conclusion Detection TTD in blood recipients before transfusion can provide useful information of infection of TTD in this area,while can ensure the rights of doctors and patients by avoiding the medical dispute and nosocomial infection resulted from the transfusion.