维持性血液透析患者血常规、钙、磷、甲状旁腺激素检测指标的调查分析

目的调查分析维持性血液透析患者的血常规、血清钙、磷及甲状旁腺激素检测指标,为临床治疗提供依据。方法抽取患者透析前空腹静脉血,检测血常规、钙、磷和甲状旁腺激素。采用血细胞分析仪检测血常规各项指标;采用血生化自动分析仪检测血清钙和磷;采用化学发光仪检测甲状旁腺激素。结果 100例男性患者中,血红蛋白(Hb)<135g/L者84例,占84.00%。76例女性患者中,Hb<120g/L者68例,占89.47%。患者血清校正钙浓度平均为(2.26±0.29)mmol/L,达标142例,占80.68%。血清磷平均浓度为(1.69±0.48)mmol/L,达标30例,占17.05%。钙、磷代谢乘积平均为(3.88±1.36)mmol/L,达标37例,占21.02%。结论维持性血液透析患者普遍存在轻度贫血,粒系和血小板基本正常。患者血清钙磷检测结果表现为低钙高磷。贫血和血清钙呈负相关性,与血清磷及钙、磷乘积无相关性。血清钙、磷乘积和甲状旁腺激素具有一定的相关性,甲状旁腺激素异常者的钙磷乘积异常率明显高于甲状旁腺激素正常人群。

Analysis for complete blood count,serum calcium,phosphorus and parathormone in patients with maintenance hemodialysis

Objective To analyze laboratory results of whole blood count,serum calcium,phosphorus and parathormone in patients with maintenance hemodialysis,so as to provide evidence for clinic therapy.Methods Fasting Blood sample was taken from patient before hemodialysis.Whole blood count was analyzed by blood cell analyzer.Serum calcium and phosphorus were analyzed by biochemical analyzer.Parathormone was analyzed by chemiluminescence analyzer.Results Male patients with hemoglobin lower than 135g/L were 84,taking 84.00%.Female patients with hemoglobin lower than 120 g/L were 68,taking 89.47%.Average serum corrected calcium concentration was 2.26±0.29mmol/L,142 patients reached standard,counting for 81.61%.Average serum phosphorus concentration was（1.69 ±0.48）mmol/L,30 patients reached standard,counting for 17.05%.Average product of calcium and phosphorus was 3.88±1.36 mmol/L,37 patients reached standard,counting for 21.02%.Conclusion Patients with maintenance hemodialysis commonly have a mild anemia and normal granulocytes and platelet.Serum calcium concentration is commonly lower,while phosphorus concentration is commonly higher.Anemia has negative correlation with serum calcium and no correlation with phosphorus and product of calcium and phosphorus.Serum product of calcium and phosphorush has correlation with IPTH,and patients with abnormal iPTH concentration has higher abnormal product of calcium and phosphorus compared with patients with normal iPTH concentration.