| Ca~(2+)-CaN-NFAT信号通路在心肌肥大中的作用及研究进展 |
| |
| 引用本文： | 蒋青松,周岐新,黄燮南. Ca~(2+)-CaN-NFAT信号通路在心肌肥大中的作用及研究进展[J]. 心血管病学进展, 2005, 0(Z1) |
| |
| 作者姓名： | 蒋青松 周岐新 黄燮南 |
| |
| 作者单位： | 重庆医科大学药理教研室 重庆400016(蒋青松，周岐新)，遵义医学院药理教研室 贵州遵义563003(黄燮南) |
| |
| 摘 要： | 钙调神经磷酸酶(calcineurin,CaN)是Ca2 的下游因子,在细胞内钙升高引起的心肌肥大中有重要作用。现综述Ca2 CaN及其下游因子活化T细胞核因子3(NFAT3)和锌指转录因子(GATA4)在心肌肥大中的作用及近年的研究进展。
|
| 关 键 词： | 钙调神经磷酸酶 心肌肥大 信号通路 |
Role of Ca~(2+)-CaN-NFAT Signaling Pathways in Cardiac Hypertrophy |
| |
| JIANG Qing-song,ZHOU Qi-xin,HUANG Xie-nan. Role of Ca~(2+)-CaN-NFAT Signaling Pathways in Cardiac Hypertrophy[J]. Advances in Cardiovascular Diseases, 2005, 0(Z1) |
| |
| Authors: | JIANG Qing-song ZHOU Qi-xin HUANG Xie-nan |
| |
| Affiliation: | JIANG Qing-song1,ZHOU Qi-xin1,HUANG Xie-nan2 |
| |
| Abstract: | Calcineurin is the downstream factor of calcium,which is involved in the cardiac hypertrophy induced by elevating intracellular calcium.In the article,the advances in studing on the calcinerurin and its downstream factor,nuclear factor of activated T cell 3 (NFAT3) and GATA4 in cardiac hypertrophy were summarized. |
| |
| Keywords: | Calcineurin Cardiac hypertrophy Signal pathway |
| 本文献已被 CNKI 等数据库收录！ |
