Serum Immunoglobulin G Antibody Responses to Bordetella pertussis Lipooligosaccharide and B. parapertussis Lipopolysaccharide in Children with Pertussis and Parapertussis |
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| Authors: | Birger Trollfors Teresa Lagergrd John Taranger Elisabet Bergfors Rachel Schneerson and John B Robbins |
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| Institution: | Birger Trollfors, Teresa Lagergård, John Taranger, Elisabet Bergfors, Rachel Schneerson, and John B. Robbins |
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| Abstract: | Serum immunoglobulin G (IgG) antibodies against the lipooligosaccharide (LOS) of Bordetella pertussis and the lipopolysaccharide (LPS) of Bordetella parapertussis were measured by enzyme-linked immunosorbent assay in paired sera from 40 children with pertussis and 14 with parapertussis. Wide differences in the individual responses were noted. Both anti-LOS and -LPS IgG levels increased significantly in the children with pertussis, as did anti-LPS but not anti-LOS in those with parapertussis. |
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