广州地区骨量峰值的调查研究

目的　研究广州城乡居民骨量峰值及其特点和影响中青年妇女骨量的因素 ,为原发骨质疏松症的诊断和预防提供有用的数据。方法　随机抽取广州地区 2 0～ 4 9岁城乡正常男女性居民 4 80人 ,先行问卷调查再进行腰椎 (L2～ 4 )正位和髋部的双能X线骨密度 (BMD)的测量。结果　男性腰椎和髋部骨量峰值 (PBM)出现在 2 0～ 2 9岁 ,L2～ 4 的PBM值为 1 14 0± 0 0 12 9(g cm2 ) ,BMD随年龄增长而下降。女性腰椎和髋部PBM出现在 30～ 39岁 (髋部的Ward’s区出现在 2 0～ 2 9岁 ) ,L2～ 4 的PBM为 1 138± 0 0 99(g cm2 ) ,男女性无显著差异。髋部PBM男性高于女性差异有显著性。 4 0～ 4 9岁不论L2～ 4 和髋部BMD女性都高于男性差异有显著性。妊娠、分娩、哺乳、避孕药、输卵管结扎术对骨量影响无显著性。结论　广州地区女性的PBM近似北京及上海地区高于成都地区。 4 0～ 4 9岁女性腰椎及髋部BMD都高于男性 ,可能与广州地区女性从事较重农业劳动有关。男性则低于沈阳、北京、上海而高于成都

An investigation of peak bone mass of residents in Guangzhou

Objective To investigate peak bone mass in residents of Guangzhou and factors influencing bone mass in young and middle|aged women,providing useful data for diagnosis and prevention of osteoporosis. Methods Bone mineral density(BMD) of 480 healthy subjects, 20|49 years old, was measured randomly,using dual|energy X|ray absorptiometry.240 of them were residents in urban area,and the other 240 were farmers in rural area.They were divided into 3 age groups by every ten years. Results Peak bone mass(PBM) of lumbar vertebrae and hip occurred in 20|29 year|old group of men(1^4+0^0129g/cm 2 for L 2|4 ),but their BMD dropped promptly with increasing age.PBM of lumbar spines(1^138+0^099 g/cm 2)and hip in women occurred in 30|39 yeare of age (that of Ward's triangle in 20|29 years).PBM of hip in men was significantly higher than that in women,while BMDs of L 2|4 and hip in women in 40|49 years of age were significantly higher than those in men.BMD of the females was not affected by pregnancy,parturition,suckling,contraceptive and fallopian tube ligation. Conclusion PBM of female residents in Guangzhou is higher than that in Chengdu,and close to that in Beijing or Shanghai,but lower than that in Shenyang,PBM of male residents in Guangzhou is higher than that in Chengdu,but lower than that in Beijing,Shanghai or Shenyang.