| ER PR及Her-2在乳腺癌中的表达及预后分析 |
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| 引用本文： | 吕金梅. ER PR及Her-2在乳腺癌中的表达及预后分析[J]. 长治医学院学报, 2010, 24(4) |
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| 作者姓名： | 吕金梅 |
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| 作者单位： | 阳泉市第一人民医院,045000 |
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| 摘 要： | 目的:探讨雌激素受体(ER)、孕激素受体(PR)及Her-2蛋白在乳腺浸润性导管癌中的表达及预后分析.方法:应用免疫组化SP法检测66例乳腺浸润性导管癌ER、PR、Her-2的表达.结果:ER的阳性表达与肿瘤的TNM分期和淋巴结转移呈负相关;PR的阳性表达与肿瘤的TNM分期和淋巴结转移无相关性;Her-2蛋白的阳性表达与肿瘤的TNM分期和淋巴结转移及肿瘤的复发呈正相关.结论:ER、PR、Her-2联合免疫组化检测是判断乳腺癌预后的重要指标.
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| 关 键 词： | 乳腺癌 激素受体 癌基因 |
Expression of ER,PR,Her-2 in Breast Cancer and Prognosis |
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| Lü Jinmei. Expression of ER,PR,Her-2 in Breast Cancer and Prognosis[J]. Journal of Changzhi Medical College, 2010, 24(4) |
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| Authors: | Lü Jinmei |
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| Abstract: | Objective:To study the expression of estrogen receptor(ER),progestogen receptor(PR)and Her-2 in breast invasive ductal carcinoma(IDC) and prognosis.Methods: Expression of ER,PR Her-2 of 66 invasive ductal carcinoma patients were determined by immunohistochemical staining.Results: The expression of ER was negayively correlated with TNM stage and lymph nodes metastasis.The expression of PR was not correlated with TNM stage and lymph nodes metastasis.The expression of Her-2 was correlated with TNM stage and ly... |
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| Keywords: | Breast cancer ER Oncogene |
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