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Issues in the management of endocarditis caused by resistant gram-positive organisms
Authors:Martin E Stryjewski  Vivian H Chu  Christopher H Cabell  Jr" target="_blank">Vance G FowlerJr
Institution:(1) Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Room 34228 Red Zone Duke South, Box 3281, 27710 Durham, NC, USA
Abstract:Most cases of infective endocarditis (IE) are caused by gram-positive bacteria such as enterococci, streptococci, and staphylococci. Increasing resistance among these organisms has eroded the utility of mainstay antibiotics and complicated the management of this difficult-to-treat infection. Clinical experience with newer gram-positive antibiotics to treat IE is limited.
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