首页 | 本学科首页   官方微博 | 高级检索  
     


Investigations on Carnitine Derivatives in Human Seminal Fluid
Authors:J. Frankel  L. M. Lewin
Affiliation:Dept. of Chemical Pathology, Sackler Medical School, Tel Aviv University, Tel Hashomer, Israel
Abstract:Free L-carnitine and its derivatives, present in human seminal fluid, were fractionated on Dowex 50WX8 (H +) cation exchange columns by sequential elution with HCl (1 M, 2.5 M and 4 M). Free L-carnitine eluted with 1 M HCl, whereas other carnitine-containing materials eluted with 2.5 M and 4 M HCl. Chromatography of semen extracts on Whatman No 1 paper likewise resolved three classes of materials which satisfied the carnitine requirement of Torulopsis bovina ATCC 26014. In addition to water soluble alkali-hydrolyzable materials with the properties of short chain acylcarnitines, there was another carnitine derivative, resistant to hydrolysis, which eluted from Dowex 50 W columns with 4 M HCl. It was concluded the human semen contains free carnitine. short chain acylcarnitines and an unidentified highly polar carnitine derivative.
Keywords:Carnitine    acylcarnitines    semen    seminal fluid
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号