孤立肾并复杂性结石的治疗选择

目的探讨孤立肾并复杂性结石的处理方式,提高其治疗的有效性和安全性。方法总结42例孤立肾并复杂性结石的治疗经验。其中先天性4例(10％)、后天原因38例(90％);左侧16例(38％)、右侧26例(62％)。均为铸形或鹿角状、多发性结石,8例合并输尿管结石,6例因急性梗阻性无尿入院;铸形或鹿角状结石首选体外震波碎石(ESWL)后经皮肾镜取石(PCNL)治疗,多发性结石先行PCNL后ESWL处理,部分病例配合腔内碎石。结果36例(86％)经ESWL及PCNL联合治疗获愈,11例PCNL术中辅以腔内碎石,6例梗阻性无尿者急诊ESWL或腔内碎石后12h内恢复排尿;6例(14％)因肾盂输尿管畸形、梗阻改行开放手术,2例继发反复感染需长期肾造瘘。37例获随访6～18个月,32例(86％)肾功能良好、5例(14％)存在肾功能不全,4例(11％)结石复发。结论联合应用ESWL及PCNL可安全有效地清除多数孤立肾的复杂性结石;肾性梗阻性无尿者行急诊ESWL是必要的,对输尿管下段梗阻性结石可首选腔内碎石;伴肾盂明显畸形或输尿管连接部严重狭窄者以选择开放手术为宜。

The treatment choice of solitary kidney complicated with complex calculi report of 42 cases

OBJECTIVE: To investigate the therapeutics of complex calculi in solitary kidney, and to improve the effect and safety of treatment. METHODS: Experiences in the treatment of 42 patients were summarized. All patients were with mould or multiple calculi, 8 cases were complicated with ureter calculi, and 6 cases were hospitalized because of obstructive anuria. The patients with mould calculi received extracorporal shock wave lithotripsy (ESWL) prior to percutaneous nephrolithotomy (PCNL). While the patients with multiple calculi received PCNL prior to ESWL. Some cases were treated by lithotripsy. RESULTS: Thirty-six cases (86%) were cured by ESWL combined with PCNL. Eleven cases received lithotripsy during PCNL. The 6 cases with obstructive anuria recovered in 12 hours after emergent ESWL or lithotripsy; 6 cases (14%) underwent open operation because of deformity or obstruction in renal pelvis and ureter; 2 cases have to keep nephrostomy because of repeated infection. Followed up 6-18 months, 38 cases (86%) keep good kidney function; 5 cases (14%) had renal insufficiency; 4 cases (11%) reoccurred calculi. CONCLUSIONS: The therapeutics of ESWL combined with PCNL may clear complex calculi of solitary kidney effectively and safe. It is necessary to take emergent ESWL in renal obstructive calculi cases. And the patients with lower ureter obstructive calculi may take lithotripsy first. It is proper to choose open operation on the patients with deformity of renal pelvis or obstruction of ureter.